Hans-Christoph Pape

Department of Orthopedic Surgery, University of Aachen Medical Center

Affiliated withUniversity of Aachen Medical Center

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
$Pseudofracture: An Acute Peripheral Tissue Trauma Model$ Publication title Cited by 38	2011

Other Publications

Article	Year
Growth factor release following femoral nailing. Bone\| PubMed ID: 18243089	2008
When should we operate on major fractures in patients with severe head injuries? American journal of surgery\| PubMed ID: 11943123	2002
Standardized outcome evaluation after blunt multiple injuries by scoring systems: a clinical follow-up investigation 2 years after injury. The Journal of trauma\| PubMed ID: 12045647	2002
The timing of fracture treatment in polytrauma patients: relevance of damage control orthopedic surgery. American journal of surgery\| PubMed ID: 12095590	2002
The effect of dehydroepiandrosterone on hemorrhage-induced suppression of cellular immune function. Intensive care medicine\| PubMed ID: 12122537	2002
Depletion of NK cells in a murine polytrauma model is associated with improved outcome and a modulation of the inflammatory response. Shock (Augusta, Ga.)\| PubMed ID: 18391857	2008
A modified method to culture human osteoblasts from bone tissue specimens using fibrin glue. Experimental and toxicologic pathology : official journal of the Gesellschaft fÃ¼r Toxikologische Pathologie\| PubMed ID: 12180798	2002
Changes in the management of femoral shaft fractures in polytrauma patients: from early total care to damage control orthopedic surgery. The Journal of trauma\| PubMed ID: 12352480	2002
Effects of intramedullary femoral fracture fixation: what is the impact of experimental studies in regards to the clinical knowledge? Shock (Augusta, Ga.)\| PubMed ID: 12392270	2002
Influence of beta-adrenoceptor antagonists on hemorrhage-induced cellular immune suppression. Shock (Augusta, Ga.)\| PubMed ID: 12392276	2002
Damage control orthopedics: a case report. The Journal of trauma\| PubMed ID: 12394881	2002
Dehydroepiandrosterone (DHEA) modulates the activity and the expression of lymphocyte subpopulations induced by cecal ligation and puncture. Shock (Augusta, Ga.)\| PubMed ID: 12412624	2002
Upper sympathetic trunk lesion after video-assisted fracture stabilization of the thoracic spine: a case report. Journal of spinal disorders & techniques\| PubMed ID: 12468978	2002
Polymicrobial sepsis induces organ changes due to granulocyte adhesion in a murine two hit model of trauma. Experimental and toxicologic pathology : official journal of the Gesellschaft fÃ¼r Toxikologische Pathologie\| PubMed ID: 12484557	2002
Effects of cardiac contusion in isolated perfused rat hearts. Shock (Augusta, Ga.)\| PubMed ID: 12578119	2003
The importance of systemic cytokines in the pathogenesis of polymicrobial sepsis and dehydroepiandrosterone treatment in a rodent model. Shock (Augusta, Ga.)\| PubMed ID: 14501948	2003
Hemorrhage in pelvic fracture: who needs angiography? Current opinion in critical care\| PubMed ID: 14639072	2003
Functional outcome following scapulothoracic dissociation. The Journal of bone and joint surgery. American volume\| PubMed ID: 14711938	2004
Improved comfort in lower limb lengthening with the intramedullary skeletal kinetic distractor. Principles and preliminary clinical experiences. Archives of orthopaedic and trauma surgery\| PubMed ID: 14745566	2004
Pathophysiologic changes and effects of hypothermia on outcome in elective surgery and trauma patients. American journal of surgery\| PubMed ID: 15006564	2004
Combination of femoral fracture treatment and corrective osteotomy in a child with osteogenesis imperfecta. Archives of orthopaedic and trauma surgery\| PubMed ID: 15034724	2004
Total hip arthroplasty in young patients using the thrust plate prosthesis: clinical and radiological results. Archives of orthopaedic and trauma surgery\| PubMed ID: 15085357	2004
Damage control: extremities. Injury\| PubMed ID: 15203308	2004
L-selectin shows time and gender dependency in association with MODS. Injury\| PubMed ID: 15488497	2004
Management of polytraumatized patients with associated blunt chest trauma: a comparison of two European countries. Injury\| PubMed ID: 15664594	2005
Does traumatic brain injury result in accelerated fracture healing? Injury\| PubMed ID: 15710151	2005
The multiply injured child. Clinical orthopaedics and related research\| PubMed ID: 15738812	2005
Improvements in passive car safety led to decreased injury severity--a comparison between the 1970s and 1990s. Injury\| PubMed ID: 15755428	2005
Secondary effects of femoral instrumentation on pulmonary physiology in a standardised sheep model: what is the effect of lung contusion and reaming? Injury\| PubMed ID: 15755438	2005
Alterations in the systemic inflammatory response after early total care and damage control procedures for femoral shaft fracture in severely injured patients. The Journal of trauma\| PubMed ID: 15761335	2005
The current status of road user injuries among the elderly in Germany: a medical and technical accident analysis. The Journal of trauma\| PubMed ID: 15761356	2005
Role of adhesion molecule ICAM in the pathogenesis of polymicrobial sepsis. Experimental and toxicologic pathology : official journal of the Gesellschaft fÃ¼r Toxikologische Pathologie\| PubMed ID: 15816357	2005
Damage control orthopaedics: evolving concepts in the treatment of patients who have sustained orthopaedic trauma. Instructional course lectures\| PubMed ID: 15948472	2005
Implant retention and removal after internal fixation of the symphysis pubis. Injury\| PubMed ID: 15949483	2005
Limb lengthening with the Intramedullary Skeletal Kinetic Distractor (ISKD). Operative OrthopÃ¤die und Traumatologie\| PubMed ID: 16007380	2005
Effects of hypothermia and re-warming on the inflammatory response in a murine multiple hit model of trauma. Cytokine\| PubMed ID: 16099670	2005
Timing of fixation of major fractures in blunt polytrauma: role of conventional indicators in clinical decision making. Journal of orthopaedic trauma\| PubMed ID: 16118563	2005
Reamed femoral nailing in sheep: does irrigation and aspiration of intramedullary contents alter the systemic response? The Journal of bone and joint surgery. American volume\| PubMed ID: 16264129	2005
Genetic predisposition for a compromised immune system after multiple trauma. Shock (Augusta, Ga.)\| PubMed ID: 16317381	2005
Staged management and outcome of combined pelvic and liver trauma. An international experience of the deadly duo. Injury\| PubMed ID: 16427639	2006
Which AIS based scoring system is the best predictor of outcome in orthopaedic blunt trauma patients? The Journal of trauma\| PubMed ID: 16508492	2006
Impact of hypothermia on the immunologic response after trauma and elective surgery. Surgical technology international\| PubMed ID: 16525953	2005
Are the protective effects of 17beta-estradiol on splenic macrophages and splenocytes after trauma-hemorrhage mediated via estrogen-receptor (ER)-alpha or ER-beta? Journal of leukocyte biology\| PubMed ID: 16531562	2006
Confusion regarding method of patient selection. The Journal of trauma\| PubMed ID: 16531878	2006
Leukocyte-endothelial interactions via ICAM-1 are detrimental in polymicrobial sepsis. Shock (Augusta, Ga.)\| PubMed ID: 16552357	2006
The risk of local infective complications after damage control procedures for femoral shaft fracture. Journal of orthopaedic trauma\| PubMed ID: 16648699	2006
Immediate fracture fixation--which method? Comments on the John Border Memorial Lecture, Ottawa, 2005. Journal of orthopaedic trauma\| PubMed ID: 16766938	2006
Effects of 17beta-estradiol and flutamide on inflammatory response and distant organ damage following trauma-hemorrhage in metestrus females. Journal of leukocyte biology\| PubMed ID: 16895975	2006
Kupffer cells and their mediators: the culprits in producing distant organ damage after trauma-hemorrhage. The American journal of pathology\| PubMed ID: 16936255	2006
Fat embolism and IM nailing. Injury\| PubMed ID: 16990056	2006
Fat embolism: special situations bilateral femoral fractures and pathologic femoral fractures. Injury\| PubMed ID: 16990057	2006
Experimental background--review of animal studies. Injury\| PubMed ID: 16990058	2006
Fat embolism: the reaming controversy. Injury\| PubMed ID: 16990061	2006
Safety and efficacy of vena cava filters in trauma patients. Injury\| PubMed ID: 17070525	2007
Effects of 17beta-estradiol and flutamide on splenic macrophages and splenocytes after trauma-hemorrhage. Cytokine\| PubMed ID: 17207634	2006
Influence of sex and age on mods and cytokines after multiple injuries. Shock (Augusta, Ga.)\| PubMed ID: 17224789	2007
Application of clinical proteomics in diagnosis and management of trauma patients. Injury\| PubMed ID: 17291504	2007
Timing and duration of the initial pelvic stabilization after multiple trauma in patients from the German trauma registry: is there an influence on outcome? The Journal of trauma\| PubMed ID: 17297327	2007
Long term results of compartment syndrome of the lower limb in polytraumatised patients. Injury\| PubMed ID: 17306263	2007
Association of IL-8-251A/T polymorphism with incidence of Acute Respiratory Distress Syndrome (ARDS) and IL-8 synthesis after multiple trauma. Cytokine\| PubMed ID: 17498967	2007
Pelvic stabilization. Prehospital management of traumatic pelvic injuries. JEMS : a journal of emergency medical services\| PubMed ID: 17631209	2007
FTY720 improves survival after transient ischemia and reperfusion of the hind limbs. The Journal of trauma\| PubMed ID: 17693822	2007
Impact of the method of initial stabilization for femoral shaft fractures in patients with multiple injuries at risk for complications (borderline patients). Annals of surgery\| PubMed ID: 17717453	2007
Mechanism of salutary effects of finasteride on post-traumatic immune/inflammatory response: upregulation of estradiol synthesis. Annals of surgery\| PubMed ID: 17968177	2007
Trauma and immune reactivity: too much, or too little immune response? Injury\| PubMed ID: 18021778	2007
Assessment of the clinical course with inflammatory parameters. Injury\| PubMed ID: 18048038	2007
Keratinocyte-derived chemokine plays a critical role in the induction of systemic inflammation and tissue damage after trauma-hemorrhage. Shock (Augusta, Ga.)\| PubMed ID: 18084824	2007
Femoral nailing-related coagulopathy determined by first-hit magnitude: an animal study. Clinical orthopaedics and related research\| PubMed ID: 18196434	2008
Biological enhancement of bone healing with Bone Morphogenetic Protein-7 at the clinical setting of pelvic girdle non-unions. Injury\| PubMed ID: 18224736	2007
External adjuncts to enhance fracture healing: what is the role of ultrasound? Injury\| PubMed ID: 18417130	2008
Local exposure of bone components to injured soft tissue induces Toll-like receptor 4-dependent systemic inflammation with acute lung injury. Shock (Augusta, Ga.)\| PubMed ID: 18461022	2008
MRI is unnecessary to clear the cervical spine in obtunded/comatose trauma patients: the four-year experience of a level I trauma center. The Journal of trauma\| PubMed ID: 18469647	2008
Effects of changing strategies of fracture fixation on immunologic changes and systemic complications after multiple trauma: damage control orthopedic surgery. Journal of orthopaedic research : official publication of the Orthopaedic Research Society\| PubMed ID: 18524013	2008
Use of the 'reamer irrigator aspirator' system for non-infected tibial non-union after failed iliac crest grafting. Injury\| PubMed ID: 18541244	2008
Patterns of cytokine release and evolution of remote organ dysfunction after bilateral femur fracture. Shock (Augusta, Ga.)\| PubMed ID: 18562923	2008
The role of fracture-associated soft tissue injury in the induction of systemic inflammation and remote organ dysfunction after bilateral femur fracture. Journal of orthopaedic trauma\| PubMed ID: 18594302	2008
Animal models for trauma research: what are the options? Shock (Augusta, Ga.)\| PubMed ID: 18636048	2009
Missed injuries in trauma patients: A literature review. Patient safety in surgery\| PubMed ID: 18721480	2008
Correlation between IL-6 levels and the systemic inflammatory response score: can an IL-6 cutoff predict a SIRS state? The Journal of trauma\| PubMed ID: 18784579	2008
Case report: The prone reduction of a sacroiliac disruption with a pelvic C-clamp. Clinical orthopaedics and related research\| PubMed ID: 18810568	2009
IL-10 deficiency augments acute lung but not liver injury in hemorrhagic shock. Cytokine\| PubMed ID: 19010691	2009
High-energy foot and ankle trauma: principles for formulating an individualized care plan. Foot and ankle clinics\| PubMed ID: 19013404	2008
History of open wound and fracture treatment. Journal of orthopaedic trauma\| PubMed ID: 19034158	2008
Current thought regarding the mechanism of action of negative pressure wound therapy with reticulated open cell foam. Journal of orthopaedic trauma\| PubMed ID: 19034159	2008
Exercise induced compartment syndrome of the pectoralis major/deltoid in a professional tree climber. Journal of shoulder and elbow surgery / American Shoulder and Elbow Surgeons ... [et al.]\| PubMed ID: 19036611	2009
Systemic inflammatory response after extremity or truncal fracture operations. The Journal of trauma\| PubMed ID: 19077630	2008
30 years of polytrauma care: An analysis of the change in strategies and results of 4849 cases treated at a single institution. Injury\| PubMed ID: 19117558	2009
Insulin therapy induces changes in the inflammatory response in a murine 2-hit model. Injury\| PubMed ID: 19167710	2009
Restricted duty hours for surgeons and impact on residents quality of life, education, and patient care: a literature review. Patient safety in surgery\| PubMed ID: 19232105	2009
Early diagnosis of tibial compartment syndrome: continuous pressure measurement or not? Injury\| PubMed ID: 19281978	2009
Introduction: Biology and new technical trends in intramedullary nailing of the femur. Journal of orthopaedic trauma\| PubMed ID: 19390368	2009
Intraoperative reduction techniques for difficult femoral fractures. Journal of orthopaedic trauma\| PubMed ID: 19390376	2009
Patterns of mortality and causes of death in polytrauma patients--has anything changed? Injury\| PubMed ID: 19540488	2009
Is dopexamine superior to dopamine in the treatment of multiple trauma patients--a prospective, double-blind, randomised study. Injury\| PubMed ID: 19595327	2010
Reduction in mortality of severely injured patients in Germany. Deutsches Ã„rzteblatt international\| PubMed ID: 19629200	2008
Timing of fracture fixation in multitrauma patients: the role of early total care and damage control surgery. The Journal of the American Academy of Orthopaedic Surgeons\| PubMed ID: 19726738	2009
Current theories on the pathophysiology of multiple organ failure after trauma. Injury\| PubMed ID: 19729158	2010
Risk of symptomatic heterotopic ossification following plate osteosynthesis in multiple trauma patients: an analysis in a level-1 trauma centre. Scandinavian journal of trauma, resuscitation and emergency medicine\| PubMed ID: 19825174	2009
Complex extremity fractures following high energy injuries: the limited value of existing classifications and a proposal for a treatment-guide. Injury\| PubMed ID: 19895956	2009
Clinical re-examination 10 or more years after polytrauma: is there a gender related difference? The Journal of trauma\| PubMed ID: 19996800	2010
Technical tricks when using the reamer irrigator aspirator technique for autologous bone graft harvesting. Journal of orthopaedic trauma\| PubMed ID: 20035177	2010
Peer teaching: a randomised controlled trial using student-teachers to teach musculoskeletal ultrasound. Medical education\| PubMed ID: 20040056	2010
Autologous bone graft: properties and techniques. Journal of orthopaedic trauma\| PubMed ID: 20182233	2010
Predictors of late clinical outcome following orthopedic injuries after multiple trauma. The Journal of trauma\| PubMed ID: 20489671	2010
A civilian perspective on ballistic trauma and gunshot injuries. Scandinavian journal of trauma, resuscitation and emergency medicine\| PubMed ID: 20565804	2010
Role of hemorrhage in the induction of systemic inflammation and remote organ damage: analysis of combined pseudo-fracture and hemorrhagic shock. Journal of orthopaedic research : official publication of the Orthopaedic Research Society\| PubMed ID: 20690183	2011
The timing of definitive fixation for major fractures in polytrauma--a matched-pair comparison between a US and European level I centres: analysis of current fracture management practice in ... Injury\| PubMed ID: 20701910	2011
Health-related quality of life in patients with multiple injuries and traumatic brain injury 10+ years postinjury. The Journal of trauma\| PubMed ID: 20838121	2010
Pattern of release and relationship between HMGB-1 and IL-6 following blunt trauma. Injury\| PubMed ID: 20887988	2010
RIA: The journey just started but what the future holds? Injury\| PubMed ID: 21144921	2010
The biology of intramedullary reaming. Injury\| PubMed ID: 21144926	2010
Measuring depression and PTSD after trauma: common scales and checklists. Injury\| PubMed ID: 21216400	2011
Scoring systems for outcome after knee injuries. Injury\| PubMed ID: 21237460	2011
Flexible fixation with locking plates. Journal of orthopaedic trauma\| PubMed ID: 21248554	2011
Effects of near cortical slotted holes in locking plate constructs. Journal of orthopaedic trauma\| PubMed ID: 21248558	2011
Models of lower extremity damage in mice: time course of organ damage and immune response. The Journal of surgical research\| PubMed ID: 21276982	2011
Head injury in polytrauma-Is there an effect on outcome more than 10 years after the injury? Brain injury : [BI]\| PubMed ID: 21534733	2011
Periprosthetic fractures: epidemiology and future projections. Journal of orthopaedic trauma\| PubMed ID: 21566478	2011
Upper extremity periarticular fractures: when should they be fixed and when should they be replaced? Journal of orthopaedic trauma\| PubMed ID: 21566482	2011
Socio-economic outcome after blunt orthopaedic trauma: Implications on injury prevention. Patient safety in surgery\| PubMed ID: 21569475	2011
Impact of Isolated Acetabular and Lower Extremity Fractures on Long-Term Outcome. The Journal of trauma\| PubMed ID: 21610530	2011
Caspase-1 is hepatoprotective during trauma and hemorrhagic shock by reducing liver injury and inflammation. Molecular medicine (Cambridge, Mass.)\| PubMed ID: 21666957	2011
The role of stem cells in fracture healing and nonunion. International orthopaedics\| PubMed ID: 21863226	2011
Effects of pelvic volume changes on retroperitoneal and intra-abdominal pressure in the injured pelvic ring: a cadaveric model. The Journal of trauma\| PubMed ID: 21908997	2011
Challenges and barriers to improving care of the musculoskeletal patient of the future - a debate article and global perspective. Patient safety in surgery\| PubMed ID: 21943304	2011
Inhalative IL-10 attenuates pulmonary inflammation following hemorrhagic shock without major alterations of the systemic inflammatory response. Mediators of inflammation\| PubMed ID: 22046081	2012
Knowledge transfer of spinal manipulation skills by student-teachers: a randomised controlled trial. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society\| PubMed ID: 22223196	2012
Is Helical Blade Nailing Superior to Locked Minimally Invasive Plating in Unstable Pertrochanteric Fractures? Clinical orthopaedics and related research\| PubMed ID: 22311725	2012