Elaine Dzierzak

Department of Cell Biology and Genetics, Erasmus University Medical Center

Affiliated withErasmus University Medical Center

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 19	2008

Other Publications

Article	Year
Stromal cell lines from mouse aorta-gonads-mesonephros subregions are potent supporters of hematopoietic stem cell activity. Blood\| PubMed ID: 11830464	2002
Expression of the Ly-6A (Sca-1) lacZ transgene in mouse haematopoietic stem cells and embryos. British journal of haematology\| PubMed ID: 11841445	2002
Ontogeny and genetics of the hemato/lymphopoietic system. Current opinion in immunology\| PubMed ID: 11869891	2002
Embryonal subregion-derived stromal cell lines from novel temperature-sensitive SV40 T antigen transgenic mice support hematopoiesis. Journal of cell science\| PubMed ID: 11973351	2002
Runx1 expression marks long-term repopulating hematopoietic stem cells in the midgestation mouse embryo. Immunity\| PubMed ID: 12049718	2002
Hematopoietic stem cells localize to the endothelial cell layer in the midgestation mouse aorta. Immunity\| PubMed ID: 12049719	2002
Ectopic expression of TAL-1 protein in Ly-6E.1-htal-1 transgenic mice induces defects in B- and T-lymphoid differentiation. Blood\| PubMed ID: 12091340	2002
Hematopoietic stem cells and their precursors: developmental diversity and lineage relationships. Immunological reviews\| PubMed ID: 12366688	2002
Comparative study of stromal cell lines derived from embryonic, fetal, and postnatal mouse blood-forming tissues. Experimental hematology\| PubMed ID: 12384152	2002
Identification of 2 novel genes developmentally regulated in the mouse aorta-gonad-mesonephros region. Blood\| PubMed ID: 12433684	2003
The Ly-6A (Sca-1) GFP transgene is expressed in all adult mouse hematopoietic stem cells. Stem cells (Dayton, Ohio)\| PubMed ID: 12456959	2002
Impaired hematopoiesis in mice lacking the transcription factor Sp3. Blood\| PubMed ID: 12676787	2003
Ontogenic emergence of definitive hematopoietic stem cells. Current opinion in hematology\| PubMed ID: 12690291	2003
The role of apoptosis in the development of AGM hematopoietic stem cells revealed by Bcl-2 overexpression. Blood\| PubMed ID: 14962910	2004
Cell-cell contact and anatomical compatibility in stromal cell-mediated HSC support during development. Stem cells (Dayton, Ohio)\| PubMed ID: 15153602	2004
Generation of murine stromal cell lines: models for the microenvironment of the embryonic mouse aorta-gonads-mesonephros region. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 15361662	2005
GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells. The Journal of experimental medicine\| PubMed ID: 15466621	2004
Hematopoietic stem cell enrichment from the AGM region of the mouse embryo. Methods in molecular medicine\| PubMed ID: 15492400	2005
Embryonic beginnings of adult hematopoietic stem cells. Haematologica\| PubMed ID: 15642676	2005
Mesenchymal progenitor cells localize within hematopoietic sites throughout ontogeny. Development (Cambridge, England)\| PubMed ID: 15689383	2005
The murine placenta contains hematopoietic stem cells within the vascular labyrinth region. Developmental cell\| PubMed ID: 15737933	2005
The emergence of definitive hematopoietic stem cells in the mammal. Current opinion in hematology\| PubMed ID: 15867575	2005
Sca-1 negatively regulates proliferation and differentiation of muscle cells. Developmental biology\| PubMed ID: 15901485	2005
Long-term maintenance of hematopoietic stem cells does not require contact with embryo-derived stromal cells in cocultures. Stem cells (Dayton, Ohio)\| PubMed ID: 15917480	2005
Multipotential hematopoietic progenitor cells from embryos developed in vitro engraft unconditioned W41/W41 neonatal miceB. Haematologica\| PubMed ID: 15951285	2005
An unexpected role for IL-3 in the embryonic development of hematopoietic stem cells. Developmental cell\| PubMed ID: 16890157	2006
Coordinated acquisition of inhibitory and activating receptors and functional properties by developing human natural killer cells. Blood\| PubMed ID: 16902150	2006
Promotion of haematopoietic activity in embryonic stem cells by the aorta-gonad-mesonephros microenvironment. Experimental cell research\| PubMed ID: 16952354	2006
Mesenchymal lineage potentials of aorta-gonad-mesonephros stromal clones. Haematologica\| PubMed ID: 16956815	2006
Bcl-2 expression and apoptosis in the regulation of hematopoietic stem cells. Leukemia & lymphoma\| PubMed ID: 17325844	2007
Embryonic stromal clones reveal developmental regulators of definitive hematopoietic stem cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18087045	2007
Of lineage and legacy: the development of mammalian hematopoietic stem cells. Nature immunology\| PubMed ID: 18204427	2008
Stem cell researchers find their niche. Development (Cambridge, England)\| PubMed ID: 18408169	2008
Fine-tuning of hematopoietic stem cell homeostasis: novel role for ubiquitin ligase. Genes & development\| PubMed ID: 18413709	2008
Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1. The EMBO journal\| PubMed ID: 18528438	2008
The discovery of a source of adult hematopoietic cells in the embryo. Development (Cambridge, England)\| PubMed ID: 18567845	2008
Efficient hematopoietic differentiation of human embryonic stem cells on stromal cells derived from hematopoietic niches. Cell stem cell\| PubMed ID: 18593561	2008
Analysis and manipulation of hematopoietic progenitor and stem cells from murine embryonic tissues. Current protocols in stem cell biology\| PubMed ID: 18770635	2008
Interleukin-1-mediated hematopoietic cell regulation in the aorta-gonad-mesonephros region of the mouse embryo. Blood\| PubMed ID: 18805969	2008
Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter. Nature\| PubMed ID: 19129762	2009
Interleukin-1 regulates hematopoietic progenitor and stem cells in the midgestation mouse fetal liver. Haematologica\| PubMed ID: 19229053	2009
Analysis of the mouse placenta as a hematopoietic stem cell niche. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19277584	2009
Hematopoietic stem cell development is dependent on blood flow. Cell\| PubMed ID: 19450519	2009
Ventral embryonic tissues and Hedgehog proteins induce early AGM hematopoietic stem cell development. Development (Cambridge, England)\| PubMed ID: 19570846	2009
Opening act in a hematopoietic program. Blood\| PubMed ID: 19589927	2009
Identification of novel regulators of hematopoietic stem cell development through refinement of stem cell localization and expression profiling. Blood\| PubMed ID: 19794138	2009
Human placenta is a potent hematopoietic niche containing hematopoietic stem and progenitor cells throughout development. Cell stem cell\| PubMed ID: 19796619	2009
In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium. Nature\| PubMed ID: 20154729	2010
Placenta as a source of hematopoietic stem cells. Trends in molecular medicine\| PubMed ID: 20580607	2010
The placenta as a haematopoietic organ. The International journal of developmental biology\| PubMed ID: 20711987	2010
Preparation of hematopoietic stem and progenitor cells from the human placenta. Current protocols in stem cell biology\| PubMed ID: 20814938	2010
Three-dimensional cartography of hematopoietic clusters in the vasculature of whole mouse embryos. Development (Cambridge, England)\| PubMed ID: 20876651	2010
Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators. Cell stem cell\| PubMed ID: 20887958	2010
Maintenance of HSC by Wnt5a secreting AGM-derived stromal cell line. Experimental hematology\| PubMed ID: 20933051	2011
The EMT regulator Zeb2/Sip1 is essential for murine embryonic hematopoietic stem/progenitor cell differentiation and mobilization. Blood\| PubMed ID: 21355089	2011
CD41 is developmentally regulated and differentially expressed on mouse hematopoietic stem cells. Blood\| PubMed ID: 21415271	2011
Isolation and analysis of hematopoietic stem cells from mouse embryos. Methods in molecular medicine\| PubMed ID: 21437797	2002
Three-dimensional imaging of whole midgestation murine embryos shows an intravascular localization for all hematopoietic clusters. Blood\| PubMed ID: 21505195	2011
A Role for PML in Innate Immunity. Genes & cancer\| PubMed ID: 21779477	2011
Erythroid/myeloid progenitors and hematopoietic stem cells originate from distinct populations of endothelial cells. Cell stem cell\| PubMed ID: 22136929	2011
Whole-mount three-dimensional imaging of internally localized immunostained cells within mouse embryos. Nature protocols\| PubMed ID: 22322215	2012