Alfredo Nicosia

Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II

Affiliated withUniversity of Naples Federico II CEINGE Biotecnologie Avanzate Franco Salvatore S.C.aR.L.ImGen-T Srl

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 12	2021
Publication title	2025

Other Publications

Article	Year
Hepatitis C virus-multispecific T-cell responses without viremia or seroconversion among Egyptian health care workers at high risk of infection. Clinical and vaccine immunology : CVI\| PubMed ID: 22441392	2012
ChAd63-MVA-vectored blood-stage malaria vaccines targeting MSP1 and AMA1: assessment of efficacy against mosquito bite challenge in humans. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 23089736	2012
Comparative analysis of the magnitude, quality, phenotype, and protective capacity of simian immunodeficiency virus gag-specific CD8+ T cells following human-, simian-, and chimpanzee-derive... Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23390298	2013
Vaccination to conserved influenza antigens in mice using a novel Simian adenovirus vector, PanAd3, derived from the bonobo Pan paniscus. PloS one\| PubMed ID: 23536756	2013
Vaccine-elicited human T cells recognizing conserved protein regions inhibit HIV-1. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 24166483	2014
Hypervariable region 1 deletion and required adaptive envelope mutations confer decreased dependency on scavenger receptor class B type I and low-density lipoprotein receptor for hepatitis C... Journal of virology\| PubMed ID: 24257605	2014
Protective CD8+ T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation. Nature communications\| PubMed ID: 24284865	2013
Fusion of HCV nonstructural antigen to MHC class II-associated invariant chain enhances T-cell responses induced by vectored vaccines in nonhuman primates. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 24476798	2014
Combined adenovirus vector and hepatitis C virus envelope protein prime-boost regimen elicits T cell and neutralizing antibody immune responses. Journal of virology\| PubMed ID: 24599994	2014
Adenovirus type 4 and 7 vaccination or adenovirus type 4 respiratory infection elicits minimal cross-reactive antibody responses to nonhuman adenovirus vaccine vectors. Clinical and vaccine immunology : CVI\| PubMed ID: 24623627	2014
Production and characterization of high-titer serum-free cell culture grown hepatitis C virus particles of genotype 1-6. Virology\| PubMed ID: 24928051	2014
Enhanced vaccine-induced CD8+ T cell responses to malaria antigen ME-TRAP by fusion to MHC class ii invariant chain. PloS one\| PubMed ID: 24945248	2014
T-cell immunity and hepatitis C virus reinfection after cure of chronic hepatitis C with an interferon-free antiviral regimen in a chimpanzee. Hepatology (Baltimore, Md.)\| PubMed ID: 24975498	2014
Role of hypervariable region 1 for the interplay of hepatitis C virus with entry factors and lipoproteins. Journal of virology\| PubMed ID: 25142595	2014
Combining viral vectored and protein-in-adjuvant vaccines against the blood-stage malaria antigen AMA1: report on a phase 1a clinical trial. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 25156127	2014
Chimpanzee adenovirus vaccine generates acute and durable protective immunity against ebolavirus challenge. Nature medicine\| PubMed ID: 25194571	2014
Evaluation of the efficacy of ChAd63-MVA vectored vaccines expressing circumsporozoite protein and ME-TRAP against controlled human malaria infection in malaria-naive individuals. The Journal of infectious diseases\| PubMed ID: 25336730	2015
Dramatic potentiation of the antiviral activity of HIV antibodies by cholesterol conjugation. The Journal of biological chemistry\| PubMed ID: 25342747	2014
A human vaccine strategy based on chimpanzee adenoviral and MVA vectors that primes, boosts, and sustains functional HCV-specific T cell memory. Science translational medicine\| PubMed ID: 25378645	2014
Chimpanzee Adenovirus Vector Ebola Vaccine. The New England journal of medicine\| PubMed ID: 25426834	2017
A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA. The New England journal of medicine\| PubMed ID: 25629663	2016
Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling. The Journal of clinical investigation\| PubMed ID: 25642773	2015
Anti-CD81 but not anti-SR-BI blocks Plasmodium falciparum liver infection in a humanized mouse model. The Journal of antimicrobial chemotherapy\| PubMed ID: 25656410	2015
Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against Plasmodium falciparum infection in Kenyan adults. Science translational medicine\| PubMed ID: 25947165	2015
Chimpanzee adenovirus- and MVA-vectored respiratory syncytial virus vaccine is safe and immunogenic in adults. Science translational medicine\| PubMed ID: 26268313	2015
Cholesterol conjugation potentiates the antiviral activity of an HIV immunoadhesin. Journal of peptide science : an official publication of the European Peptide Society\| PubMed ID: 26292842	2015
Targeting a host-cell entry factor barricades antiviral-resistant HCV variants from on-therapy breakthrough in human-liver mice. Gut\| PubMed ID: 26306759	2016
Chronic hepatitis C viral infection subverts vaccine-induced T-cell immunity in humans. Hepatology (Baltimore, Md.)\| PubMed ID: 26474390	2016
Persistent HCV replication despite priming of functional CD8+ T cells by combined therapy with a vaccine and direct acting antiviral. Hepatology (Baltimore, Md.)\| PubMed ID: 26513111	2015
Novel human anti-claudin 1 mAbs inhibit hepatitis C virus infection and may synergize with anti-SRB1 mAb. The Journal of general virology\| PubMed ID: 26519290	2016
Safety and Immunogenicity of ChAd63 and MVA ME-TRAP in West African Children and Infants. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 27109630	2016
Highly-Immunogenic Virally-Vectored T-cell Vaccines Cannot Overcome Subversion of the T-cell Response by HCV during Chronic Infection. Vaccines\| PubMed ID: 27490575	2016
Therapeutic Vaccine Against Primate Papillomavirus Infections of the Cervix. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 28166180	2017
Mucosal Vaccination with Heterologous Viral Vectored Vaccine Targeting Subdominant SIV Accessory Antigens Strongly Inhibits Early Viral Replication. EBioMedicine\| PubMed ID: 28302457	2017
Human vaccination against Plasmodium vivax Duffy-binding protein induces strain-transcending antibodies. JCI insight\| PubMed ID: 28614791	2017
Chimpanzee adenoviral vectors as vaccines - challenges to move the technology into the fast lane. Expert review of vaccines\| PubMed ID: 29047309	2017
Incidence and Risk Factors for Hepatitis C Virus Infection among Illicit Drug Users in Italy. Journal of urban health : bulletin of the New York Academy of Medicine\| PubMed ID: 29204843	2018
Assessment of novel vaccination regimens using viral vectored liver stage malaria vaccines encoding ME-TRAP. Scientific reports\| PubMed ID: 29467399	2018
Immune Profiling of Premalignant Lesions in Patients With Lynch Syndrome. JAMA oncology\| PubMed ID: 29710228	2018
Massive parallel screening of phage libraries for the generation of repertoires of human immunomodulatory monoclonal antibodies. mAbs\| PubMed ID: 29995563	2018
Antigen-specific CD8 T cells in cell cycle circulate in the blood after vaccination. Scandinavian journal of immunology\| PubMed ID: 30488973	2019
A Novel Vaccine Strategy Employing Serologically Different Chimpanzee Adenoviral Vectors for the Prevention of HIV-1 and HCV Coinfection. Frontiers in immunology\| PubMed ID: 30713538	2018
Novel genetically-modified chimpanzee adenovirus and MVA-vectored respiratory syncytial virus vaccine safely boosts humoral and cellular immunity in healthy older adults. The Journal of infection\| PubMed ID: 30742894	2019
Longitudinal transcriptomic and genetic landscape of radiotherapy response in canine melanoma. Veterinary and comparative oncology\| PubMed ID: 30805995	2019
Adenoviral vaccine targeting multiple neoantigens as strategy to eradicate large tumors combined with checkpoint blockade. Nature communications\| PubMed ID: 31217437	2019
Novel Human Anti-PD-L1 mAbs Inhibit Immune-Independent Tumor Cell Growth and PD-L1 Associated Intracellular Signalling. Scientific reports\| PubMed ID: 31511565	2019
Rapid Affinity Maturation of Novel Anti-PD-L1 Antibodies by a Fast Drop of the Antigen Concentration and FACS Selection of Yeast Libraries. BioMed research international\| PubMed ID: 31976323	2019
MHC class II invariant chain-adjuvanted viral vectored vaccines enhances T cell responses in humans. Science translational medicine\| PubMed ID: 32554708	2020
A Genetic Vaccine Encoding Shared Cancer Neoantigens to Treat Tumors with Microsatellite Instability. Cancer research\| PubMed ID: 32690723	2020
Isolation of Two Novel Human Anti-CTLA-4 mAbs with Intriguing Biological Properties on Tumor and NK Cells. Cancers\| PubMed ID: 32781690	2020
Optimising T cell (re)boosting strategies for adenoviral and modified vaccinia Ankara vaccine regimens in humans. NPJ vaccines\| PubMed ID: 33083029	2020
Integrity of the Antiviral STING-mediated DNA Sensing in Tumor Cells Is Required to Sustain the Immunotherapeutic Efficacy of Oncolytic Virus. Cancers\| PubMed ID: 33213060	2020
New viral vectors for infectious diseases and cancer. Seminars in immunology\| PubMed ID: 33262065	2020
Peptide nucleic acid-mediated circularization of target RNA as tool to inhibit translation. International journal of biological macromolecules\| PubMed ID: 40118420	2025