Shijun Wang

Shanghai Institute of Cardiovascular Diseases, Fudan University

Affiliated withFudan University Shandong University of Traditional Chinese Medicine Shandong Co-Innovation Center of Classic TCM Formula, Shandong Provincial Education Department

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 3	2022
Publication title Cited by 9	2021

Other Publications

Article	Year
Antidepressant mechanism of classical herbal formula lily bulb and Rehmannia decoction: insights from gene expression profile of medial prefrontal cortex of mice with stress-induced depressi... Genes, brain, and behavior\| PubMed ID: 32129566	2020
Artery interposed to vein did not develop atherosclerosis and underwent atrophic remodeling in cholesterol-fed rabbits. Atherosclerosis\| PubMed ID: 15488863	2004
Enhanced myocardial cathepsin B expression in patients with dilated cardiomyopathy. European journal of heart failure\| PubMed ID: 16480925	2006
Emodin induces growth arrest and death of human vascular smooth muscle cells through reactive oxygen species and p53. Journal of cardiovascular pharmacology\| PubMed ID: 17513942	2007
[Research on medical speciality of traditional Chinese medicines using dot-immunoblotting method based on polyclonal antibody prepared from traditional Chinese medicines with hot/cold nature... Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica\| PubMed ID: 19459307	2009
Molecular and clinical characterization of a novel SCN5A mutation associated with atrioventricular block and dilated cardiomyopathy. Circulation. Arrhythmia and electrophysiology\| PubMed ID: 19808398	2008
Another possible cell source for cardiac regenerative medicine: reprogramming adult fibroblasts to cardiomyocytes and endothelial progenitor cells. Medical hypotheses\| PubMed ID: 21087827	2011
Inhibition of aldehyde dehydrogenase 2 activity enhances antimycin-induced rat cardiomyocytes apoptosis through activation of MAPK signaling pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 21123025	2011
Salvianolic acid B suppresses maturation of human monocyte-derived dendritic cells by activating PPARÎ³. British journal of pharmacology\| PubMed ID: 21649636	2011
[Effects of aconite root on energy metabolism and expression of related genes in rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica\| PubMed ID: 22256761	2011
Up-regulation of BMP-2 antagonizes TGF-β1/ROCK-enhanced cardiac fibrotic signalling through activation of Smurf1/Smad6 complex. Journal of cellular and molecular medicine\| PubMed ID: 22283839	2012
[Influence of Aconiti Lateralis Radix Praeparata on asthenia cold syndrome rats with whole genome gene expression of liver by gene chip technique]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica\| PubMed ID: 22667152	2012
Danhong inhibits oxidized low-density lipoprotein-induced immune maturation of dentritic cells via a peroxisome proliferator activated receptor γ-mediated pathway. Journal of pharmacological sciences\| PubMed ID: 22739234	2012
Olmesartan attenuates cardiac remodeling through DLL4/Notch1 pathway activation in pressure overload mice. Journal of cardiovascular pharmacology\| PubMed ID: 23188126	2013
Naoxintong protects against atherosclerosis through lipid-lowering and inhibiting maturation of dendritic cells in LDL receptor knockout mice fed a high-fat diet. Current pharmaceutical design\| PubMed ID: 23438960	2013
Gene expression profiling of rat livers with yin-deficiency-heat syndrome. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan\| PubMed ID: 24024336	2013
Aldehyde dehydrogenase 2 ameliorates doxorubicin-induced myocardial dysfunction through detoxification of 4-HNE and suppression of autophagy. Journal of molecular and cellular cardiology\| PubMed ID: 24434637	2014
Src is required for mechanical stretch-induced cardiomyocyte hypertrophy through angiotensin II type 1 receptor-dependent β-arrestin2 pathways. PloS one\| PubMed ID: 24699426	2014
Insights into the activation and inhibition of angiotensin II type 1 receptor in the mechanically loaded heart. Circulation journal : official journal of the Japanese Circulation Society\| PubMed ID: 24813328	2014
Mitochondrial aldehyde dehydrogenase 2 plays protective roles in heart failure after myocardial infarction via suppression of the cytosolic JNK/p53 pathway in mice. Journal of the American Heart Association\| PubMed ID: 25237043	2014
A protective role of ciglitazone in ox-LDL-induced rat microvascular endothelial cells via modulating PPARγ-dependent AMPK/eNOS pathway. Journal of cellular and molecular medicine\| PubMed ID: 25388834	2015
CXCR6 deficiency attenuates pressure overload-induced monocytes migration and cardiac fibrosis through downregulating TNF-α-dependent MMP9 pathway. International journal of clinical and experimental pathology\| PubMed ID: 25400729	2014
Qiliqiangxin inhibits angiotensin II-induced transdifferentiation of rat cardiac fibroblasts through suppressing interleukin-6. Journal of cellular and molecular medicine\| PubMed ID: 25752645	2015
Combination Treatment With Antihypertensive Agents Enhances the Effect of Qiliqiangxin on Chronic Pressure Overload-induced Cardiac Hypertrophy and Remodeling in Male Mice. Journal of cardiovascular pharmacology\| PubMed ID: 25806688	2015
Electro-acupuncture up-regulates astrocytic MCT1 expression to improve neurological deficit in middle cerebral artery occlusion rats. Life sciences\| PubMed ID: 26037401	2015
Letter to the editor: When what you see might not be what you get: prudent considerations of anesthetics for murine echocardiography. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 26078381	2015
Qiliqiangxin improves cardiac function and attenuates cardiac remodeling in rats with experimental myocardial infarction. International journal of clinical and experimental pathology\| PubMed ID: 26261541	2015
Identification of Amino Acid Residues in Angiotensin II Type 1 Receptor Sensing Mechanical Stretch and Function in Cardiomyocyte Hypertrophy. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology\| PubMed ID: 26303226	2015
The effects of different angiotensin II type 1 receptor blockers on the regulation of the ACE-AngII-AT1 and ACE2-Ang(1-7)-Mas axes in pressure overload-induced cardiac remodeling in male mic... Journal of molecular and cellular cardiology\| PubMed ID: 27210827	2016
Aldehyde dehydrogenase 2 deficiency blunts compensatory cardiac hypertrophy through modulating Akt phosphorylation early after transverse aorta constriction in mice. Biochimica et biophysica acta\| PubMed ID: 27239698	2016
Mitochondrial PKC-ε deficiency promotes I/R-mediated myocardial injury via GSK3β-dependent mitochondrial permeability transition pore opening. Journal of cellular and molecular medicine\| PubMed ID: 28266127	2017
Ultrasound biomicroscopy validation of a murine model of cardiac hypertrophic preconditioning: comparison with a hemodynamic assessment. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 28455286	2017
MECHANISMS OF COIX SEED COMPOSITIONS IN THE TREATMENT OF SPLEEN DEFICIENCY AND WET DAMPNESS ZHENG. African journal of traditional, complementary, and alternative medicines : AJTCAM\| PubMed ID: 28638886	2017
Efficacy of low carbohydrate diet for type 2 diabetes mellitus management: A systematic review and meta-analysis of randomized controlled trials. Diabetes research and clinical practice\| PubMed ID: 28750216	2017
Differential cardiac hypertrophy and signaling pathways in pressure versus volume overload. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 29196344	2018
HSF1 deficiency accelerates the transition from pressure overload-induced cardiac hypertrophy to heart failure through endothelial miR-195a-3p-mediated impairment of cardiac angiogenesis. Journal of molecular and cellular cardiology\| PubMed ID: 29626503	2018
Electroacupunture contributes to recovery of neurological deficits in experimental stroke by activating astrocytes. Restorative neurology and neuroscience\| PubMed ID: 29758953	2018
Evaluation of the performance of serum miRNAs as normalizers in microRNA studies focused on cardiovascular disease. Journal of thoracic disease\| PubMed ID: 29997921	2018
The Effects of Radix Astragali Water Abstract on Energy Metabolism in Rat Yang-Deficiency Cold Syndrome Model through PPAR Signaling Pathway. Evidence-based complementary and alternative medicine : eCAM\| PubMed ID: 30519272	2018
Metabolomics Research Reveals the Mechanism of Action of Astragalus Polysaccharide in Rats with Digestive System Disorders. Molecules (Basel, Switzerland)\| PubMed ID: 30558291	2018
Anti-Inflammatory Effect of IL-37-Producing T-Cell Population in DSS-Induced Chronic Inflammatory Bowel Disease in Mice. International journal of molecular sciences\| PubMed ID: 30563054	2018
Chinese Herbal Medicine Wenxia Changfu Formula Reverses Cell Adhesion-Mediated Drug Resistance via the Integrin β1-PI3K-AKT Pathway in Lung Cancer. Journal of Cancer\| PubMed ID: 30719123	2019
Research progress on classical traditional Chinese medicine formula Lily Bulb and Rehmannia Decoction in the treatment of depression. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 30780102	2019
Identification of key genes, pathways, and miRNA/mRNA regulatory networks of CUMS-induced depression in nucleus accumbens by integrated bioinformatics analysis. Neuropsychiatric disease and treatment\| PubMed ID: 30936699	2019
High-Resistant Starch, Low-Protein Flour Intervention on Patients With Early Type 2 Diabetic Nephropathy: A Randomized Trial. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation\| PubMed ID: 30982743	2019
Beta-elemene inhibits breast cancer metastasis through blocking pyruvate kinase M2 dimerization and nuclear translocation. Journal of cellular and molecular medicine\| PubMed ID: 31343107	2019
Peroxisome Proliferator-Activated Receptor-γ Antagonizes LOX-1-Mediated Endothelial Injury by Transcriptional Activation of miR-590-5p. PPAR research\| PubMed ID: 31354796	2019
A Complex Role for Calcium Signaling in Colorectal Cancer Development and Progression. Molecular cancer research : MCR\| PubMed ID: 31366605	2019
The molecular mechanism underlying GABAergic dysfunction in nucleus accumbens of depression-like behaviours in mice. Journal of cellular and molecular medicine\| PubMed ID: 31430030	2019
Oroxylin A induces apoptosis of activated hepatic stellate cells through endoplasmic reticulum stress. Apoptosis : an international journal on programmed cell death\| PubMed ID: 31538267	2019
Oroxylin A regulates the turnover of lipid droplet via downregulating adipose triglyceride lipase (ATGL) in hepatic stellate cells. Life sciences\| PubMed ID: 31610205	2019
Innate Lymphoid Cells: Regulators of Gut Barrier Function and Immune Homeostasis. Journal of immunology research\| PubMed ID: 31930146	2019
Liver regeneration in traditional Chinese medicine: advances and challenges. Regenerative medicine research\| PubMed ID: 31939733	2020
Curcumol attenuates liver sinusoidal endothelial cell angiogenesis via regulating Glis-PROX1-HIF-1α in liver fibrosis. Cell proliferation\| PubMed ID: 32119185	2020
Transforming growth factor β1 is a differentially expressed candidate protein of congestive heart failure with Qi-deficiency-blood-stasis syndrome. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan\| PubMed ID: 32242397	2020
A novel lncRNA PLK4 up-regulated by talazoparib represses hepatocellular carcinoma progression by promoting YAP-mediated cell senescence. Journal of cellular and molecular medicine\| PubMed ID: 32243714	2020
Oroxylin a promotes PGC-1α/Mfn2 signaling to attenuate hepatocyte pyroptosis via blocking mitochondrial ROS in alcoholic liver disease. Free radical biology & medicine\| PubMed ID: 32289481	2020
Left ventricular response in the transition from hypertrophy to failure recapitulates distinct roles of Akt, β-arrestin-2, and CaMKII in mice with aortic regurgitation. Annals of translational medicine\| PubMed ID: 32309366	2020
Zi Shen Huo Luo Formula Enhances the Therapeutic Effects of Angiotensin-Converting Enzyme Inhibitors on Hypertensive Left Ventricular Hypertrophy by Interfering With Aldosterone Breakthrough... Frontiers in pharmacology\| PubMed ID: 32317965	2020
Blockade of periostin-dependent migration and adhesion by curcumol via inhibition of nuclear factor kappa B signaling in hepatic stellate cells. Toxicology\| PubMed ID: 32344006	2020
HIF-1α-upregulated lncRNA-H19 regulates lipid droplet metabolism through the AMPKα pathway in hepatic stellate cells. Life sciences\| PubMed ID: 32445757	2020
Protective effects of cardiac resynchronization therapy in a canine model with experimental heart failure by improving mitochondrial function: a mitochondrial proteomics study. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing\| PubMed ID: 32488750	2021
Chinese herbal medicine Baoyuan Jiedu decoction inhibits the accumulation of myeloid derived suppressor cells in pre-metastatic niche of lung via TGF-β/CCL9 pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 32554250	2020
The BRD7-P53-SLC25A28 axis regulates ferroptosis in hepatic stellate cells. Redox biology\| PubMed ID: 32863216	2020
Iron regulatory protein 2 is required for artemether -mediated anti-hepatic fibrosis through ferroptosis pathway. Free radical biology & medicine\| PubMed ID: 32947011	2020
Novel copper complex CTB regulates methionine cycle induced TERT hypomethylation to promote HCC cells senescence via mitochondrial SLC25A26. Cell death & disease\| PubMed ID: 33041323	2020
From the perspective of Traditional Chinese Medicine: Treatment of mental disorders in COVID-19 survivors. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 33053508	2020
Regulation of hepatic stellate cell contraction and cirrhotic portal hypertension by Wnt/β-catenin signalling via interaction with Gli1. British journal of pharmacology\| PubMed ID: 33085791	2021
Curcumol inhibits KLF5-dependent angiogenesis by blocking the ROS/ERK signaling in liver sinusoidal endothelial cells. Life sciences\| PubMed ID: 33157090	2021
Variations in Energy Metabolism Precede Alterations in Cardiac Structure and Function in Hypertrophic Preconditioning. Frontiers in cardiovascular medicine\| PubMed ID: 33426002	2020
Depression with Comorbid Diabetes: What Evidence Exists for Treatments Using Traditional Chinese Medicine and Natural Products? Frontiers in pharmacology\| PubMed ID: 33568996	2020
ShengMai-San Attenuates Cardiac Remodeling in Diabetic Rats by Inhibiting NOX-Mediated Oxidative Stress. Diabetes, metabolic syndrome and obesity : targets and therapy\| PubMed ID: 33603429	2021
Activation of CXCL16/CXCR6 axis aggravates cardiac ischemia/reperfusion injury by recruiting the IL-17a-producing CD1d T cells. Clinical and translational medicine\| PubMed ID: 33634988	2021
Research progress on the pharmacological effect and clinical application of Tongqiao Huoxue Decoction in the treatment of ischaemic stroke. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 33711554	2021
Coix lacryma-jobi Seed Oil Reduces Fat Accumulation in Nonalcoholic Fatty Liver Disease by Inhibiting the Activation of the p-AMPK/SePP1/apoER2 Pathway. Journal of oleo science\| PubMed ID: 33840662	2021
20()-ginsenoside Rh2 induces caspase-dependent promyelocytic leukemia-retinoic acid receptor A degradation in NB4 cells via Akt/Bax/caspase9 and TNF-α/caspase8 signaling cascades. Journal of ginseng research\| PubMed ID: 33841010	2021
Caspase-1 Abrogates the Salutary Effects of Hypertrophic Preconditioning in Pressure Overload Hearts via IL-1β and IL-18. Frontiers in molecular biosciences\| PubMed ID: 33842546	2021
Fluorescence live cell imaging revealed wogonin targets mitochondria. Talanta\| PubMed ID: 33934785	2021
Cryptotanshinone Inhibits ERα-Dependent and -Independent BCRP Oligomer Formation to Reverse Multidrug Resistance in Breast Cancer. Frontiers in oncology\| PubMed ID: 33968724	2021
Hypertrophic preconditioning attenuates post-myocardial infarction injury through deacetylation of isocitrate dehydrogenase 2. Acta pharmacologica Sinica\| PubMed ID: 34163022	2021
Interleukin-18 accelerates cardiac inflammation and dysfunction during ischemia/reperfusion injury by transcriptional activation of CXCL16. Cellular signalling\| PubMed ID: 34487815	2021
PCSK9 participates in oxidized-low density lipoprotein-induced myocardial injury through mitochondrial oxidative stress and Drp1-mediated mitochondrial fission. Clinical and translational medicine\| PubMed ID: 35184412	2022
Editorial: Mitochondrial Metabolism in Ischemic Heart Disease. Frontiers in cardiovascular medicine\| PubMed ID: 35833188	2022
CXCR6 Mediates Pressure Overload-Induced Aortic Stiffness by Increasing Macrophage Recruitment and Reducing Exosome-miRNA29b. Journal of cardiovascular translational research\| PubMed ID: 36018423	2022