Marcelo D. Carattino

Renal-Electrolyte Division, University of Pittsburgh School of Medicine

Affiliated withUniversity of Pittsburgh School of Medicine University of Pittsburgh

Research Area

Biography

Marcelo D. Carattino has not added Biography.
If you are Marcelo D. Carattino and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 2	2022
Publication title	2022
Publication title Cited by 14	2023

Other Publications

Article	Year
Syntaxin 1A regulates ENaC via domain-specific interactions. The Journal of biological chemistry\| PubMed ID: 12562778	2003
Arachidonic acid regulates surface expression of epithelial sodium channels. The Journal of biological chemistry\| PubMed ID: 12837767	2003
Maturation of the epithelial Na+ channel involves proteolytic processing of the alpha- and gamma-subunits. The Journal of biological chemistry\| PubMed ID: 12871941	2003
Epithelial Na+ channels are activated by laminar shear stress. The Journal of biological chemistry\| PubMed ID: 14625286	2004
Epithelial sodium channels are activated by furin-dependent proteolysis. The Journal of biological chemistry\| PubMed ID: 15007080	2004
Mutations in the pore region modify epithelial sodium channel gating by shear stress. The Journal of biological chemistry\| PubMed ID: 15569663	2005
Epithelial sodium channel inhibition by AMP-activated protein kinase in oocytes and polarized renal epithelial cells. The Journal of biological chemistry\| PubMed ID: 15753079	2005
The epithelial Na+ channel is inhibited by a peptide derived from proteolytic processing of its alpha subunit. The Journal of biological chemistry\| PubMed ID: 16690613	2006
Epithelial Na+ channels are fully activated by furin- and prostasin-dependent release of an inhibitory peptide from the gamma-subunit. The Journal of biological chemistry\| PubMed ID: 17199078	2007
Lack of a role of membrane-protein interactions in flow-dependent activation of ENaC. American journal of physiology. Renal physiology\| PubMed ID: 17459954	2007
Role of proteolysis in the activation of epithelial sodium channels. Current opinion in nephrology and hypertension\| PubMed ID: 17693760	2007
Defining an inhibitory domain in the alpha-subunit of the epithelial sodium channel. American journal of physiology. Renal physiology\| PubMed ID: 18032549	2008
Effect of aldosterone on BK channel expression in mammalian cortical collecting duct. American journal of physiology. Renal physiology\| PubMed ID: 18579708	2008
Proteolytic processing of the epithelial sodium channel gamma subunit has a dominant role in channel activation. The Journal of biological chemistry\| PubMed ID: 18650438	2008
Novel determinants of epithelial sodium channel gating within extracellular thumb domains. The Journal of biological chemistry\| PubMed ID: 19158091	2009
ENaC at the cutting edge: regulation of epithelial sodium channels by proteases. The Journal of biological chemistry\| PubMed ID: 19401469	2009
Conformational changes associated with proton-dependent gating of ASIC1a. The Journal of biological chemistry\| PubMed ID: 19858190	2009
Defining an inhibitory domain in the gamma subunit of the epithelial sodium channel. American journal of physiology. Renal physiology\| PubMed ID: 20630937	2010
Clues to renal sodium retention. American journal of physiology. Renal physiology\| PubMed ID: 21228112	2011
Second transmembrane domain modulates epithelial sodium channel gating in response to shear stress. American journal of physiology. Renal physiology\| PubMed ID: 21307123	2011
Base of the thumb domain modulates epithelial sodium channel gating. The Journal of biological chemistry\| PubMed ID: 21367859	2011
Insights into the mechanism of pore opening of acid-sensing ion channel 1a. The Journal of biological chemistry\| PubMed ID: 21388961	2011
Structural mechanisms underlying the function of epithelial sodium channel/acid-sensing ion channel. Current opinion in nephrology and hypertension\| PubMed ID: 21709553	2011
TMPRSS4-dependent activation of the epithelial sodium channel requires cleavage of the γ-subunit distal to the furin cleavage site. American journal of physiology. Renal physiology\| PubMed ID: 21993886	2012
Contribution of residues in second transmembrane domain of ASIC1a protein to ion selectivity. The Journal of biological chemistry\| PubMed ID: 22371494	2012
Inhibitory tract traps the epithelial Na+ channel in a low activity conformation. The Journal of biological chemistry\| PubMed ID: 22511777	2012
Cation transport goes with the flow. American journal of physiology. Renal physiology\| PubMed ID: 22739535	2012
Role of the wrist domain in the response of the epithelial sodium channel to external stimuli. The Journal of biological chemistry\| PubMed ID: 23144453	2012
Gating transitions in the palm domain of ASIC1a. The Journal of biological chemistry\| PubMed ID: 23300086	2013
ENaC regulation by proteases and shear stress. Current molecular pharmacology\| PubMed ID: 23547932	2013
Bladder filling and voiding affect umbrella cell tight junction organization and function. American journal of physiology. Renal physiology\| PubMed ID: 23884145	2013
Regulation of large-conductance Ca2+-activated K+ channels by WNK4 kinase. American journal of physiology. Cell physiology\| PubMed ID: 23885063	2013
Independent contribution of extracellular proton binding sites to ASIC1a activation. The Journal of biological chemistry\| PubMed ID: 24142696	2013
Shear stress-dependent regulation of apical endocytosis in renal proximal tubule cells mediated by primary cilia. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24912170	2014
Prostasin interacts with the epithelial Na+ channel and facilitates cleavage of the γ-subunit by a second protease. American journal of physiology. Renal physiology\| PubMed ID: 25209858	2014
Intracellular Na+ regulates epithelial Na+ channel maturation. The Journal of biological chemistry\| PubMed ID: 25767115	2015
Increased urothelial paracellular transport promotes cystitis. American journal of physiology. Renal physiology\| PubMed ID: 26423859	2015
Cell-specific regulation of L-WNK1 by dietary K. American journal of physiology. Renal physiology\| PubMed ID: 26662201	2016
The Thumb Domain Mediates Acid-sensing Ion Channel Desensitization. The Journal of biological chemistry\| PubMed ID: 27015804	2016
Specific Palmitoyltransferases Associate with and Activate the Epithelial Sodium Channel. The Journal of biological chemistry\| PubMed ID: 28154191	2017
Urothelial Tight Junction Barrier Dysfunction Sensitizes Bladder Afferents. eNeuro\| PubMed ID: 28560313	2017
Expression and Analysis of Flow-regulated Ion Channels in Oocytes. Bio-protocol\| PubMed ID: 28670605	2017
Cdc42 activation couples fluid shear stress to apical endocytosis in proximal tubule cells. Physiological reports\| PubMed ID: 29038362	2017
ASIC3 fine-tunes bladder sensory signaling. American journal of physiology. Renal physiology\| PubMed ID: 29561183	2018
Molecular basis of inhibition of acid sensing ion channel 1A by diminazene. PloS one\| PubMed ID: 29782492	2018
Urinary K promotes irritative voiding symptoms and pain in the face of urothelial barrier dysfunction. Scientific reports\| PubMed ID: 30940909	2019
Renal sensory nerves increase sympathetic nerve activity and blood pressure in 2-kidney 1-clip hypertensive mice. Journal of neurophysiology\| PubMed ID: 31091159	2019
Murine epithelial sodium (Na) channel regulation by biliary factors. The Journal of biological chemistry\| PubMed ID: 31092599	2019
Expression and distribution of PIEZO1 in the mouse urinary tract. American journal of physiology. Renal physiology\| PubMed ID: 31166705	2019
Molecular determinants of afferent sensitization in a rat model of cystitis with urothelial barrier dysfunction. Journal of neurophysiology\| PubMed ID: 31314637	2019
Acid-sensing ion channels in sensory signaling. American journal of physiology. Renal physiology\| PubMed ID: 31984789	2020
Paraoxonase 3 functions as a chaperone to decrease functional expression of the epithelial sodium channel. The Journal of biological chemistry\| PubMed ID: 32079677	2020
The Urothelium: Life in a Liquid Environment. Physiological reviews\| PubMed ID: 32191559	2020
Functional roles for PIEZO1 and PIEZO2 in urothelial mechanotransduction and lower urinary tract interoception. JCI insight\| PubMed ID: 34464353	2021
Acid-sensing ion channels modulate bladder nociception. American journal of physiology. Renal physiology\| PubMed ID: 34514879	2021
Bladder infection with uropathogenic increases the excitability of afferent neurons. American journal of physiology. Renal physiology\| PubMed ID: 34779263	2022
Studies of ultrastructure, gene expression, and marker analysis reveal that mouse bladder PDGFRA interstitial cells are fibroblasts. American journal of physiology. Renal physiology\| PubMed ID: 35834272	2022
Functional characterization of ion channels expressed in kidney organoids derived from human induced pluripotent stem cells. American journal of physiology. Renal physiology\| PubMed ID: 35979965	2022