Graham Hatfull

Department of Biological Sciences, University of Pittsburgh

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 79	2012

Other Publications

Article	Year
Growth of Mycobacterium tuberculosis biofilms containing free mycolic acids and harbouring drug-tolerant bacteria. Molecular microbiology\| PubMed ID: 18466296	2008
Microbiology. A tail of two specifi-cities. Science (New York, N.Y.)\| PubMed ID: 11896263	2002
Bacteriophage Mu genome sequence: analysis and comparison with Mu-like prophages in Haemophilus, Neisseria and Deinococcus. Journal of molecular biology\| PubMed ID: 11922669	2002
Imbroglios of viral taxonomy: genetic exchange and failings of phenetic approaches. Journal of bacteriology\| PubMed ID: 12169615	2002
Integration and excision of the Mycobacterium tuberculosis prophage-like element, phiRv1. Molecular microbiology\| PubMed ID: 12354222	2002
Specialized transduction: an efficient method for generating marked and unmarked targeted gene disruptions in Mycobacterium tuberculosis, M. bovis BCG and M. smegmatis. Microbiology (Reading, England)\| PubMed ID: 12368434	2002
Corrected sequence of the bacteriophage p22 genome. Journal of bacteriology\| PubMed ID: 12562822	2003
Control of directionality in L5 integrase-mediated site-specific recombination. Journal of molecular biology\| PubMed ID: 12581642	2003
Origins of highly mosaic mycobacteriophage genomes. Cell\| PubMed ID: 12705866	2003
Bacteriophages with tails: chasing their origins and evolution. Research in microbiology\| PubMed ID: 12798229	2003
Rapid identification and susceptibility testing of Mycobacterium tuberculosis from MGIT cultures with luciferase reporter mycobacteriophages. Journal of medical microbiology\| PubMed ID: 12808076	2003
Mycobacteriophage Bxb1 integrates into the Mycobacterium smegmatis groEL1 gene. Molecular microbiology\| PubMed ID: 14617171	2003
The orientation of mycobacteriophage Bxb1 integration is solely dependent on the central dinucleotide of attP and attB. Molecular cell\| PubMed ID: 14636570	2003
The pKO2 linear plasmid prophage of Klebsiella oxytoca. Journal of bacteriology\| PubMed ID: 14996813	2004
Complete genomic sequence of the virulent Salmonella bacteriophage SP6. Journal of bacteriology\| PubMed ID: 15028677	2004
Bxz1, a new generalized transducing phage for mycobacteria. FEMS microbiology letters\| PubMed ID: 15598543	2004
The generalized transducing Salmonella bacteriophage ES18: complete genome sequence and DNA packaging strategy. Journal of bacteriology\| PubMed ID: 15659686	2005
2004 ASM Conference on the New Phage Biology: the 'Phage Summit'. Molecular microbiology\| PubMed ID: 15720541	2005
Integration and excision by the large serine recombinase phiRv1 integrase. Molecular microbiology\| PubMed ID: 15752208	2005
Synapsis in phage Bxb1 integration: selection mechanism for the correct pair of recombination sites. Journal of molecular biology\| PubMed ID: 15890199	2005
GroEL1: a dedicated chaperone involved in mycolic acid biosynthesis during biofilm formation in mycobacteria. Cell\| PubMed ID: 16325580	2005
Control of phage Bxb1 excision by a novel recombination directionality factor. PLoS biology\| PubMed ID: 16719562	2006
Exploring the mycobacteriophage metaproteome: phage genomics as an educational platform. PLoS genetics\| PubMed ID: 16789831	2006
Efficient site-specific integration in Plasmodium falciparum chromosomes mediated by mycobacteriophage Bxb1 integrase. Nature methods\| PubMed ID: 16862136	2006
Mycobacteriophage exploit NHEJ to facilitate genome circularization. Molecular cell\| PubMed ID: 16949369	2006
A peptidoglycan hydrolase motif within the mycobacteriophage TM4 tape measure protein promotes efficient infection of stationary phase cells. Molecular microbiology\| PubMed ID: 17083467	2006
Recombineering in Mycobacterium tuberculosis. Nature methods\| PubMed ID: 17179933	2007
Inquiry learning. Teaching scientific inquiry. Science (New York, N.Y.)\| PubMed ID: 17185586	2006
Genome sequence, structural proteins, and capsid organization of the cyanophage Syn5: a "horned" bacteriophage of marine synechococcus. Journal of molecular biology\| PubMed ID: 17383677	2007
Genomic and structural analysis of Syn9, a cyanophage infecting marine Prochlorococcus and Synechococcus. Environmental microbiology\| PubMed ID: 17564603	2007
Comparative genomic analysis of mycobacteriophage Tweety: evolutionary insights and construction of compatible site-specific integration vectors for mycobacteria. Microbiology (Reading, England)\| PubMed ID: 17660435	2007
The role of iron in Mycobacterium smegmatis biofilm formation: the exochelin siderophore is essential in limiting iron conditions for biofilm formation but not for planktonic growth. Molecular microbiology\| PubMed ID: 17854402	2007
Genomic characterization of mycobacteriophage Giles: evidence for phage acquisition of host DNA by illegitimate recombination. Journal of bacteriology\| PubMed ID: 18178732	2008
Efficient point mutagenesis in mycobacteria using single-stranded DNA recombineering: characterization of antimycobacterial drug targets. Molecular microbiology\| PubMed ID: 18221264	2008
Two-step site selection for serine-integrase-mediated excision: DNA-directed integrase conformation and central dinucleotide proofreading. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18299577	2008
Mycobacterial recombineering. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 18370078	2008
Exploring the prokaryotic virosphere. Research in microbiology\| PubMed ID: 18639443	2008
Comparative genomics of the mycobacteriophages: insights into bacteriophage evolution. Research in microbiology\| PubMed ID: 18653319	2008
Bacteriophage genomics. Current opinion in microbiology\| PubMed ID: 18824125	2008
Recombineering mycobacteria and their phages. Nature reviews. Microbiology\| PubMed ID: 18923412	2008
BRED: a simple and powerful tool for constructing mutant and recombinant bacteriophage genomes. PloS one\| PubMed ID: 19088849	2008
The genome of Bacillus subtilis bacteriophage SPO1. Journal of molecular biology\| PubMed ID: 19285085	2009
Fluoromycobacteriophages for rapid, specific, and sensitive antibiotic susceptibility testing of Mycobacterium tuberculosis. PloS one\| PubMed ID: 19300517	2009
Mycobacteriophage Lysin B is a novel mycolylarabinogalactan esterase. Molecular microbiology\| PubMed ID: 19555454	2009
Mycobacteriophages BPs, Angel and Halo: comparative genomics reveals a novel class of ultra-small mobile genetic elements. Microbiology (Reading, England)\| PubMed ID: 19556295	2009
Comparative genomic analysis of 60 Mycobacteriophage genomes: genome clustering, gene acquisition, and gene size. Journal of molecular biology\| PubMed ID: 20064525	2010
Do mycobacteria produce endospores? Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20080769	2010
Enzymatic hydrolysis of trehalose dimycolate releases free mycolic acids during mycobacterial growth in biofilms. The Journal of biological chemistry\| PubMed ID: 20375425	2010
Temperature-dependent regulation of mycolic acid cyclopropanation in saprophytic mycobacteria: role of the Mycobacterium smegmatis 1351 gene (MSMEG_1351) in CIS-cyclopropanation of alpha-myc... The Journal of biological chemistry\| PubMed ID: 20457615	2010
Mycobacteriophages: genes and genomes. Annual review of microbiology\| PubMed ID: 20528690	2010
Expanding the diversity of mycobacteriophages: insights into genome architecture and evolution. PloS one\| PubMed ID: 21298013	2011
Evaluation of fluoromycobacteriophages for detecting drug resistance in Mycobacterium tuberculosis. Journal of clinical microbiology\| PubMed ID: 21346042	2011
Single-molecule analysis reveals the molecular bearing mechanism of DNA strand exchange by a serine recombinase. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21502527	2011
Successive and targeted DNA integrations in the Drosophila genome by Bxb1 and phiC31 integrases. Genetics\| PubMed ID: 21652525	2011
Evaluation of a transposase protocol for rapid generation of shotgun high-throughput sequencing libraries from nanogram quantities of DNA. Applied and environmental microbiology\| PubMed ID: 21948828	2011
Phamerator: a bioinformatic tool for comparative bacteriophage genomics. BMC bioinformatics\| PubMed ID: 21991981	2011
Reporter phage and breath tests: emerging phenotypic assays for diagnosing active tuberculosis, antibiotic resistance, and treatment efficacy. The Journal of infectious diseases\| PubMed ID: 21996696	2011
Bacteriophages and their Genomes. Current opinion in virology\| PubMed ID: 22034588	2011
Cluster K mycobacteriophages: insights into the evolutionary origins of mycobacteriophage TM4. PloS one\| PubMed ID: 22053209	2011
Competencies: a cure for pre-med curriculum. Science (New York, N.Y.)\| PubMed ID: 22076362	2011
The Bxb1 gp47 recombination directionality factor is required not only for prophage excision, but also for phage DNA replication. Gene\| PubMed ID: 22227494	2012
2GFP10: A high-intensity fluorophage enables detection and rapid drug susceptibility testing of Mycobacterium tuberculosis directly from sputum samples. Journal of clinical microbiology\| PubMed ID: 22278833	2012
Complete Genome Sequences of 138 Mycobacteriophages. Journal of virology\| PubMed ID: 22282335	2012