David A. Haake

Department of Urology, University of California, Los Angeles

Affiliated withUniversity of California, Los Angeles Veterans Affairs Greater Los Angeles Healthcare System

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 6	2013
Publication title Cited by 3	2017

Other Publications

Article	Year
Novel 45-kilodalton leptospiral protein that is processed to a 31-kilodalton growth-phase-regulated peripheral membrane protein. Infection and immunity\| PubMed ID: 11748198	2002
Leptospirosis, water sports, and chemoprophylaxis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 11941571	2002
Global analysis of outer membrane proteins from Leptospira interrogans serovar Lai. Infection and immunity\| PubMed ID: 11953365	2002
Gastrointestinal microflora studies in late-onset autism. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 12173102	2002
Characterization of the leptospiral outer membrane and description of three novel leptospiral membrane proteins. Infection and immunity\| PubMed ID: 12183539	2002
An improved immunohistochemical diagnostic technique for canine leptospirosis using antileptospiral antibodies on renal tissue. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc\| PubMed ID: 12680639	2002
LipL21 is a novel surface-exposed lipoprotein of pathogenic Leptospira species. Infection and immunity\| PubMed ID: 12704111	2003
Pathogenic Leptospira species express surface-exposed proteins belonging to the bacterial immunoglobulin superfamily. Molecular microbiology\| PubMed ID: 12890019	2003
Molecular evolution and mosaicism of leptospiral outer membrane proteins involves horizontal DNA transfer. Journal of bacteriology\| PubMed ID: 15090524	2004
Outer membrane proteins of pathogenic spirochetes. FEMS microbiology reviews\| PubMed ID: 15449605	2004
Osmolarity, a key environmental signal controlling expression of leptospiral proteins LigA and LigB and the extracellular release of LigA. Infection and immunity\| PubMed ID: 15618142	2005
Rapid, species-specific detection of uropathogen 16S rDNA and rRNA at ambient temperature by dot-blot hybridization and an electrochemical sensor array. Molecular genetics and metabolism\| PubMed ID: 15639199	2005
Diagnostic and therapeutic pitfalls associated with primaquine-tolerant Plasmodium vivax. Journal of clinical microbiology\| PubMed ID: 15695723	2005
Leptospiral membrane proteins--variations on a theme? The Indian journal of medical research\| PubMed ID: 15802754	2005
Surfaceome of Leptospira spp. Infection and immunity\| PubMed ID: 16040999	2005
Electrochemical molecular analysis without nucleic acid amplification. Methods (San Diego, Calif.)\| PubMed ID: 16213156	2005
Leptospirosis after recreational exposure to water in the Yaeyama islands, Japan. The American journal of tropical medicine and hygiene\| PubMed ID: 16222003	2005
LruA and LruB, novel lipoproteins of pathogenic Leptospira interrogans associated with equine recurrent uveitis. Infection and immunity\| PubMed ID: 16239521	2005
Lipoprotein computational prediction in spirochaetal genomes. Microbiology (Reading, England)\| PubMed ID: 16385121	2006
Use of electrochemical DNA biosensors for rapid molecular identification of uropathogens in clinical urine specimens. Journal of clinical microbiology\| PubMed ID: 16455913	2006
Molecular epidemiology of leptospirosis in the Amazon. PLoS medicine\| PubMed ID: 16933961	2006
Effects of temperature on gene expression patterns in Leptospira interrogans serovar Lai as assessed by whole-genome microarrays. Infection and immunity\| PubMed ID: 16988264	2006
LipL46 is a novel surface-exposed lipoprotein expressed during leptospiral dissemination in the mammalian host. Microbiology (Reading, England)\| PubMed ID: 17159228	2006
Physiological osmotic induction of Leptospira interrogans adhesion: LigA and LigB bind extracellular matrix proteins and fibrinogen. Infection and immunity\| PubMed ID: 17296754	2007
Leptospira immunoglobulin-like proteins as a serodiagnostic marker for acute leptospirosis. Journal of clinical microbiology\| PubMed ID: 17360842	2007
Response of Leptospira interrogans to physiologic osmolarity: relevance in signaling the environment-to-host transition. Infection and immunity\| PubMed ID: 17371863	2007
Development of an advanced electrochemical DNA biosensor for bacterial pathogen detection. The Journal of molecular diagnostics : JMD\| PubMed ID: 17384207	2007
The terminal portion of leptospiral immunoglobulin-like protein LigA confers protective immunity against lethal infection in the hamster model of leptospirosis. Vaccine\| PubMed ID: 17629368	2007
Leptospira interrogans endostatin-like outer membrane proteins bind host fibronectin, laminin and regulators of complement. PloS one\| PubMed ID: 18000555	2007
Early diagnosis of leptospirosis by immunoglobulin M immunoblot testing. Clinical and vaccine immunology : CVI\| PubMed ID: 18184827	2008
Rapid antimicrobial susceptibility determination of uropathogens in clinical urine specimens by use of ATP bioluminescence. Journal of clinical microbiology\| PubMed ID: 18272708	2008
Optimal probe length and target location for electrochemical detection of selected uropathogens at ambient temperature. Journal of clinical microbiology\| PubMed ID: 18562584	2008
Hamster model of leptospirosis. Current protocols in microbiology\| PubMed ID: 18770576	2006
Uropathogens and host characteristics. Journal of clinical microbiology\| PubMed ID: 18842936	2008
Genetic diversity of the Leptospiral immunoglobulin-like (Lig) genes in pathogenic Leptospira spp. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases\| PubMed ID: 19028604	2009
An unsteady microfluidic T-form mixer perturbed by hydrodynamic pressure. Journal of micromechanics and microengineering : structures, devices, and systems\| PubMed ID: 19177174	2008
Leptospira interrogans stably infects zebrafish embryos, altering phagocyte behavior and homing to specific tissues. PLoS neglected tropical diseases\| PubMed ID: 19547748	2009
A comprehensive approach to identification of surface-exposed, outer membrane-spanning proteins of Leptospira interrogans. PloS one\| PubMed ID: 19562037	2009
Multiplex pathogen identification for polymicrobial urinary tract infections using biosensor technology: a prospective clinical study. The Journal of urology\| PubMed ID: 19837423	2009
Potentiometric detection of DNA hybridization using enzyme-induced metallization and a silver ion selective electrode. Analytical chemistry\| PubMed ID: 19908886	2009
Leptospira: a spirochaete with a hybrid outer membrane. Molecular microbiology\| PubMed ID: 20598085	2010
Transcriptional response of Leptospira interrogans to iron limitation and characterization of a PerR homolog. Infection and immunity\| PubMed ID: 20805337	2010
The OmpL37 surface-exposed protein is expressed by pathogenic Leptospira during infection and binds skin and vascular elastin. PLoS neglected tropical diseases\| PubMed ID: 20844573	2010
Ternary Surface Monolayers for Ultrasensitive (Zeptomole) Amperometric Detection of Nucleic Acid Hybridization without Signal Amplification. Analytical chemistry\| PubMed ID: 20883023	2010
Bacterial biofilm disruption using laser generated shockwaves. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference\| PubMed ID: 21096997	2010
Laser induced shockwaves on flexible polymers for treatment of bacterial biofilms. Studies in health technology and informatics\| PubMed ID: 21335826	2011
Redox cycling amplified electrochemical detection of DNA hybridization: application to pathogen E. coli bacterial RNA. Analytica chimica acta\| PubMed ID: 21338752	2011
The multifunctional LigB adhesin binds homeostatic proteins with potential roles in cutaneous infection by pathogenic Leptospira interrogans. PloS one\| PubMed ID: 21347378	2011
Ternary monolayers as DNA recognition interfaces for direct and sensitive electrochemical detection in untreated clinical samples. Biosensors & bioelectronics\| PubMed ID: 21377347	2011
Interactions of leptospira with environmental bacteria from surface water. Current microbiology\| PubMed ID: 21479795	2011
Heterologous expression of pathogen-specific genes ligA and ligB in the saprophyte Leptospira biflexa confers enhanced adhesion to cultured cells and fibronectin. BMC microbiology\| PubMed ID: 21658265	2011
Highly sensitive disposable nucleic acid biosensors for direct bioelectronic detection in raw biological samples. Talanta\| PubMed ID: 21807191	2011
Target-specific capture enhances sensitivity of electrochemical detection of bacterial pathogens. Journal of clinical microbiology\| PubMed ID: 21940468	2011
Methylation and in vivo expression of the surface-exposed Leptospira interrogans outer membrane protein OmpL32. Microbiology (Reading, England)\| PubMed ID: 22174381	2011
A LigA three-domain region protects hamsters from lethal infection by Leptospira interrogans. PLoS neglected tropical diseases\| PubMed ID: 22180800	2011
Three-Dimensional Structures of Pathogenic and Saprophytic Leptospira Revealed by Cryo-Electron Tomography. Journal of bacteriology\| PubMed ID: 22228733	2012
Antibodies to a novel leptospiral protein, LruC, in the eye fluids and sera of horses with Leptospira-associated uveitis. Clinical and vaccine immunology : CVI\| PubMed ID: 22237897	2012
Multiple leptospiral sphingomyelinases (or are there?). Microbiology (Reading, England)\| PubMed ID: 22422753	2012
FlaA proteins in Leptospira interrogans are essential for motility and virulence but are not required for formation of the flagellum sheath. Infection and immunity\| PubMed ID: 22451522	2012
Leptospiral outer membrane protein microarray, a novel approach to identification of host ligand-binding proteins. Journal of bacteriology\| PubMed ID: 22961849	2012
Rapid antimicrobial susceptibility testing by sensitive detection of precursor rRNA using a novel electrochemical biosensing platform. Antimicrobial agents and chemotherapy\| PubMed ID: 23229486	2013
LipL32 Is a Subsurface Lipoprotein of Leptospira interrogans: presentation of new data and reevaluation of previous studies. PloS one\| PubMed ID: 23323152	2013