Shelley L Berger

Department of Cell and Developmental Biology, University of Pennsylvania

Affiliated withUniversity of Pennsylvania

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 110	2013

Other Publications

Article	Year
Structural basis for histone and phosphohistone binding by the GCN5 histone acetyltransferase. Molecular cell\| PubMed ID: 14536085	2003
The SANT domain of Ada2 is required for normal acetylation of histones by the yeast SAGA complex. The Journal of biological chemistry\| PubMed ID: 11777910	2002
Histone modifications in transcriptional regulation. Current opinion in genetics & development\| PubMed ID: 11893486	2002
Trans-tail histone modifications: wedge or bridge? Nature structural biology\| PubMed ID: 12145643	2002
SALSA, a variant of yeast SAGA, contains truncated Spt7, which correlates with activated transcription. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12186975	2002
Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins. Molecular and cellular biology\| PubMed ID: 12482968	2003
A novel human Ada2 homologue functions with Gcn5 or Brg1 to coactivate transcription. Molecular and cellular biology\| PubMed ID: 12972612	2003
Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8. Genes & development\| PubMed ID: 14563679	2003
Histone modifications: Now summoning sumoylation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14597707	2003
Temporal and spatial changes in transcription factor binding and histone modifications at the steroidogenic acute regulatory protein (stAR) locus associated with stAR transcription. Molecular endocrinology (Baltimore, Md.)\| PubMed ID: 14726488	2004
Histone modification patterns during gene activation. Methods in enzymology\| PubMed ID: 14979022	2004
H2B ubiquitylation and de-ubiquitylation in gene activation. Novartis Foundation symposium\| PubMed ID: 15171247	2004
Good fences make good neighbors: barrier elements and genomic regulation. Molecular cell\| PubMed ID: 15546609	2004
H2B ubiquitin protease Ubp8 and Sgf11 constitute a discrete functional module within the Saccharomyces cerevisiae SAGA complex. Molecular and cellular biology\| PubMed ID: 15657441	2005
Histone H3 phosphorylation can promote TBP recruitment through distinct promoter-specific mechanisms. The EMBO journal\| PubMed ID: 15719021	2005
Maintenance of low histone ubiquitylation by Ubp10 correlates with telomere-proximal Sir2 association and gene silencing. Molecular cell\| PubMed ID: 15721261	2005
Phosphorylation of histone H4 serine 1 during DNA damage requires casein kinase II in S. cerevisiae. Current biology : CB\| PubMed ID: 15823538	2005
Sumoylation of the yeast Gcn5 protein. Biochemistry\| PubMed ID: 16411780	2006
Structure and dimerization of the kinase domain from yeast Snf1, a member of the Snf1/AMPK protein family. Structure (London, England : 1993)\| PubMed ID: 16531232	2006
Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications. Genes & development\| PubMed ID: 16598039	2006
Trimethylation of histone H3 lysine 4 by Set1 in the lytic infection of human herpes simplex virus 1. Journal of virology\| PubMed ID: 16731913	2006
A feed-forward repression mechanism anchors the Sin3/histone deacetylase and N-CoR/SMRT corepressors on chromatin. Molecular and cellular biology\| PubMed ID: 16809761	2006
Phosphorylation of histone H4 Ser1 regulates sporulation in yeast and is conserved in fly and mouse spermatogenesis. Genes & development\| PubMed ID: 16980586	2006
LKB1 is recruited to the p21/WAF1 promoter by p53 to mediate transcriptional activation. Cancer research\| PubMed ID: 17108107	2006
Repression of p53 activity by Smyd2-mediated methylation. Nature\| PubMed ID: 17108971	2006
In vivo dual cross-linking for identification of indirect DNA-associated proteins by chromatin immunoprecipitation. BioTechniques\| PubMed ID: 17191611	2006
CTCF-dependent chromatin boundary element between the latency-associated transcript and ICP0 promoters in the herpes simplex virus type 1 genome. Journal of virology\| PubMed ID: 17267480	2007
Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map. Nature\| PubMed ID: 17314980	2007
The complex language of chromatin regulation during transcription. Nature\| PubMed ID: 17522673	2007
H2B ubiquitylation acts as a barrier to Ctk1 nucleosomal recruitment prior to removal by Ubp8 within a SAGA-related complex. Molecular cell\| PubMed ID: 17643376	2007
p53 is regulated by the lysine demethylase LSD1. Nature\| PubMed ID: 17805299	2007
Histone H3 K4 demethylation during activation and attenuation of GAL1 transcription in Saccharomyces cerevisiae. Molecular and cellular biology\| PubMed ID: 17875926	2007
New nomenclature for chromatin-modifying enzymes. Cell\| PubMed ID: 18022353	2007
The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression. Molecular cell\| PubMed ID: 18206973	2008
14-3-3 interaction with histone H3 involves a dual modification pattern of phosphoacetylation. Molecular and cellular biology\| PubMed ID: 18268010	2008
The emerging field of dynamic lysine methylation of non-histone proteins. Current opinion in genetics & development\| PubMed ID: 18339539	2008
The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression. Genes & development\| PubMed ID: 18832071	2008
Hit and run: transient deubiquitylase activity in a chromatin-remodeling complex. Molecular cell\| PubMed ID: 18922460	2008
The histone variant H3.3 regulates gene expression during lytic infection with herpes simplex virus type 1. Journal of virology\| PubMed ID: 19004946	2009
Out of the jaws of death: PRMT5 steers p53. Nature cell biology\| PubMed ID: 19043433	2008
Protein acetylation microarray reveals that NuA4 controls key metabolic target regulating gluconeogenesis. Cell\| PubMed ID: 19303850	2009
An operational definition of epigenetics. Genes & development\| PubMed ID: 19339683	2009
Genome reprogramming during sporulation. The International journal of developmental biology\| PubMed ID: 19412896	2009
Histone H4 lysine 16 acetylation regulates cellular lifespan. Nature\| PubMed ID: 19516333	2009
Identification and characterization of novel sirtuin inhibitor scaffolds. Bioorganic & medicinal chemistry\| PubMed ID: 19734050	2009
Inactivation of the Sas2 histone acetyltransferase delays senescence driven by telomere dysfunction. The EMBO journal\| PubMed ID: 19875981	2010
G9a and Glp methylate lysine 373 in the tumor suppressor p53. The Journal of biological chemistry\| PubMed ID: 20118233	2010
Chromatin dynamics during herpes simplex virus-1 lytic infection. Biochimica et biophysica acta\| PubMed ID: 20139038	2010
Genome-wide mapping of histone H4 serine-1 phosphorylation during sporulation in Saccharomyces cerevisiae. Nucleic acids research\| PubMed ID: 20375100	2010
Keeping p53 in check: a high-stakes balancing act. Cell\| PubMed ID: 20603009	2010
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation. Science (New York, N.Y.)\| PubMed ID: 20647423	2010
Systematic screen reveals new functional dynamics of histones H3 and H4 during gametogenesis. Genes & development\| PubMed ID: 20713519	2010
Genomic comparison of the ants Camponotus floridanus and Harpegnathos saltator. Science (New York, N.Y.)\| PubMed ID: 20798317	2010
Epigenetic drugs can stimulate metastasis through enhanced expression of the pro-metastatic Ezrin gene. PloS one\| PubMed ID: 20856924	2010
Cutting edge: persistently open chromatin at effector gene loci in resting memory CD8+ T cells independent of transcriptional status. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21278341	2011
A genetic and molecular toolbox for analyzing histone ubiquitylation and sumoylation in yeast. Methods (San Diego, Calif.)\| PubMed ID: 21310241	2011
The contribution of epigenetic memory to immunologic memory. Current opinion in genetics & development\| PubMed ID: 21330128	2011
Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress. Genes & development\| PubMed ID: 21576264	2011
Acetylation of yeast AMPK controls intrinsic aging independently of caloric restriction. Cell\| PubMed ID: 21906795	2011
Histone H4 lysine 20 of Saccharomyces cerevisiae is monomethylated and functions in subtelomeric silencing. Biochemistry\| PubMed ID: 21985125	2011
MYST protein acetyltransferase activity requires active site lysine autoacetylation. The EMBO journal\| PubMed ID: 22020126	2012
H2B ubiquitylation is part of chromatin architecture that marks exon-intron structure in budding yeast. BMC genomics\| PubMed ID: 22188810	2011
Transgenerational inheritance of longevity: epigenetic mysteries abound. Cell metabolism\| PubMed ID: 22225870	2012
IDH mutation impairs histone demethylation and results in a block to cell differentiation. Nature\| PubMed ID: 22343901	2012
Gcn5p-dependent acetylation induces degradation of the meiotic transcriptional repressor Ume6p. Molecular biology of the cell\| PubMed ID: 22438583	2012
The linker histone plays a dual role during gametogenesis in Saccharomyces cerevisiae. Molecular and cellular biology\| PubMed ID: 22586276	2012
Genome-wide and caste-specific DNA methylomes of the ants Camponotus floridanus and Harpegnathos saltator. Current biology : CB\| PubMed ID: 22885060	2012
Phylogenetic and transcriptomic analysis of chemosensory receptors in a pair of divergent ant species reveals sex-specific signatures of odor coding. PLoS genetics\| PubMed ID: 22952454	2012
Low-hanging fruit: targeting Brdt in the testes. The EMBO journal\| PubMed ID: 22960636	2012
A chromatin link to caste identity in the carpenter ant Camponotus floridanus. Genome research\| PubMed ID: 23212948	2013
Social insect genomes exhibit dramatic evolution in gene composition and regulation while preserving regulatory features linked to sociality. Genome research\| PubMed ID: 23636946	2013
Genome-wide epigenetics. The Journal of investigative dermatology\| PubMed ID: 23673507	2013
Lysosome-mediated processing of chromatin in senescence. The Journal of cell biology\| PubMed ID: 23816621	2013
Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape. Genes & development\| PubMed ID: 23934658	2013